Fermez les frontières, un nouveau virus apparaît: La COVID-19
- Thread starter Jeremi01
- Start date
Sustain26
Banned
BOOM !! Le Dr David Bauer révèle les résultats de son étude : plus l'on reçoit de doses, plus notre niveau d'anticorps neutralisants diminue !! Avec 2 doses, on se retrouve avec 6 a 6 fois moins de ces anticorps qui sont les piliers de nos défenses immunitaires !! #manifs28août
https://twitter.com/VSainement
https://twitter.com/VSainement
Sustain26
Banned
Another Alternative Therapy or Preventative Therapy
Viruses are efficient metabolic engineers that actively rewire host metabolic pathways to support their lifecycle, presenting attractive metabolic targets for intervention. Here we chart the metabolic response of lung epithelial cells to SARS-CoV-2 infection in primary cultures and COVID-19 patient samples. Bulk and single-cell analyses show that viral replication induces endoplasmic stress and lipid accumulation. Protein expression screen suggests a role for viral proteins in mediating this metabolic response even in the absence of replication. Metabolism-focused drug screen showed that fenofibrate reversed lipid accumulation and blocked SARS-CoV-2 replication. Analysis of 3,233 Israeli patients hospitalized due to COVID-19 supported in vitro findings. Patients taking fibrates showed significantly lower markers of immunoinflammation and faster recovery. Additional corroboration was received by comparative epidemiological analysis from cohorts in Europe and the United States. A subsequent prospective interventional open-label study was carried out in 15 patients hospitalized with severe COVID-19. The patients were treated with 145 mg/day of nanocrystallized fenofibrate (TriCor®) in addition to standard-of-care. Patients receiving fenofibrate demonstrated a rapid reduction in inflammation and a significantly faster recovery compared to control patients admitted during the same period and treated with the standard-of-care. Taken together, our data show that elevated lipid metabolism underlies critical aspects of COVID-19 pathogenesis, suggesting that pharmacological modulation of lipid metabolism should be strongly considered for the treatment of coronavirus infection.
https://www.researchsquare.com/article/rs-770724
and
Emergency Available Drugs in Markets to Treat COVID-19
https://www.researchsquare.com/article/rs-764141/v1
Viruses are efficient metabolic engineers that actively rewire host metabolic pathways to support their lifecycle, presenting attractive metabolic targets for intervention. Here we chart the metabolic response of lung epithelial cells to SARS-CoV-2 infection in primary cultures and COVID-19 patient samples. Bulk and single-cell analyses show that viral replication induces endoplasmic stress and lipid accumulation. Protein expression screen suggests a role for viral proteins in mediating this metabolic response even in the absence of replication. Metabolism-focused drug screen showed that fenofibrate reversed lipid accumulation and blocked SARS-CoV-2 replication. Analysis of 3,233 Israeli patients hospitalized due to COVID-19 supported in vitro findings. Patients taking fibrates showed significantly lower markers of immunoinflammation and faster recovery. Additional corroboration was received by comparative epidemiological analysis from cohorts in Europe and the United States. A subsequent prospective interventional open-label study was carried out in 15 patients hospitalized with severe COVID-19. The patients were treated with 145 mg/day of nanocrystallized fenofibrate (TriCor®) in addition to standard-of-care. Patients receiving fenofibrate demonstrated a rapid reduction in inflammation and a significantly faster recovery compared to control patients admitted during the same period and treated with the standard-of-care. Taken together, our data show that elevated lipid metabolism underlies critical aspects of COVID-19 pathogenesis, suggesting that pharmacological modulation of lipid metabolism should be strongly considered for the treatment of coronavirus infection.
https://www.researchsquare.com/article/rs-770724
and
Emergency Available Drugs in Markets to Treat COVID-19
https://www.researchsquare.com/article/rs-764141/v1
O'Toole va lui jouer de la jigue irlandaise après les élections.
SRT-What?
Legacy Member
pepperidge farm remembers
Le Manitoba va l’adopter, l’Ontario aussi. La plupart des événements aux states on demande une preuve de PCR négatif ou preuve vaccinale, C’est pas mal établie en France, l’Italie adopte le siens bientôt etc
Ça va être de meme pas mal partout. C’est juste que nous, ils appellent ça passeport
Mart_IT
Legacy Member
C’est quand même bizarre vous devez avouer que plusieurs scientifique notoire, des sommités dans leurs domaine se font taire quand il s’oppose à la vaccination ou aux mesures en place.
Des généticiens, virologue et spécialiste qui se font traiter de conspirationiste s’il n’adopte pas le meme discours que le gouvernement.
J’suis pas conspirationiste mais je trouve que ça sent pas bon tout ça .
Je serait pas surpris que Grim post des shit qui vont s’avérer vrai d’ici une couple d’années..
Le rabbit hole est tellement creux et le commun des mortelles passerait sa vie à essayer d’élucider ses mystères.
Des généticiens, virologue et spécialiste qui se font traiter de conspirationiste s’il n’adopte pas le meme discours que le gouvernement.
J’suis pas conspirationiste mais je trouve que ça sent pas bon tout ça .
Je serait pas surpris que Grim post des shit qui vont s’avérer vrai d’ici une couple d’années..
Le rabbit hole est tellement creux et le commun des mortelles passerait sa vie à essayer d’élucider ses mystères.
Mickrob
Legacy Member
Quand le Delta va exploser ici et que la majorité des nouveaux cas vont être double vaccinés... quel va être la réponse a Legrault ?
Faker des stats pour mettre ca sur la faute des personnes non vacciné?
Exiger une 3e dose avant l'approbation de l'OMS?
Couvre feu a 17H?
Toutes ces réponses?
Faker des stats pour mettre ca sur la faute des personnes non vacciné?
Exiger une 3e dose avant l'approbation de l'OMS?
Couvre feu a 17H?
Toutes ces réponses?
Sustain26
Banned
https://twitter.com/i/status/1431608681519591424
Anonyme Citoyen
@AnonymeCitoyen
·
2h
Énorme manifestation à #Paris pour le septième samedi consécutif contre le #PassSanitaire. Plus de 200 manifestations dans toute la France dont 4 à Paris. (
@CharlesBaudry
) #manifestation28aout #Manif28aout
Anonyme Citoyen
@AnonymeCitoyen
·
2h
Énorme manifestation à #Paris pour le septième samedi consécutif contre le #PassSanitaire. Plus de 200 manifestations dans toute la France dont 4 à Paris. (
@CharlesBaudry
) #manifestation28aout #Manif28aout
Le Patriote
Well-known member
Dans 6 mois le grand Maitre va parler de ceux qui ont eu seulement leurs 2 doses comme si ils étaient des mauvais citoyens, responsables de morts indirectes et insouciants. Les hospitalisations seront de leurs fautes.
Les radios et télé feront leurs propagandes normales. Comme quoi la Covid c'est une affaire Québécoise seulement et que les variants qui sortent de partout sur la terre sans cesse ne nous rejoindrait pas si on avait eu nos 6iemes doses.
Envoyé de mon SM-A530W en utilisant Tapatalk
Sustain26
Banned
From the movie Network (1976):
“You have meddled with the primal forces of nature, Mr. Beale, and I won’t have it! Is that clear? You think you’ve merely stopped a business deal. That is not the case! The Arabs have taken billions of dollars out of this country, and now they must put it back! It is ebb and flow, tidal gravity! It is ecological balance!
“You are an old man who thinks in terms of nations and peoples. There are no nations. There are no peoples. There are no Russians. There are no Arabs. There are no third worlds. There is no West. There is only one holistic system of systems, one vast and immane, interwoven, interacting, multivariate, multinational dominion of dollars. Petro-dollars, electro-dollars, multi-dollars, Reich marks, rins, rubles, pounds, and shekels.
“It is the international system of currency which determines the totality of life on this planet. That is the natural order of things today. That is the atomic and subatomic and galactic structure of things today! And you have meddled with the primal forces of nature, and you… will… atone!
“Am I getting through to you, Mr. Beale?
“You get up on your little twenty-one inch screen and howl about America and democracy. There is no America. There is no democracy. There is only IBM, and ITT, and AT&T, and DuPont, Dow, Union Carbide, and Exxon. Those are the nations of the world today.
“What do you think the Russians talk about in their councils of state, Karl Marx? They get out their linear programming charts, statistical decision theories, minimax solutions, and compute the price-cost probabilities of their transactions and investments, just like we do. We no longer live in a world of nations and ideologies, Mr. Beale. The world is a college of corporations, inexorably determined by the immutable bylaws of business.
“The world is a business, Mr. Beale. It has been since man crawled out of the slime. And our children will live, Mr. Beale, to see that… perfect world… in which there’s no war or famine, oppression or brutality. One vast and ecumenical holding company, for whom all men will work to serve a common profit, in which all men will hold a share of stock. All necessities provided, all anxieties tranquilized, all boredom amused.
“And I have chosen you, Mr. Beale, to preach this evangel.”
https://theshadowzone.wordpress.com/2012/12/20/network-1976-review/
“You have meddled with the primal forces of nature, Mr. Beale, and I won’t have it! Is that clear? You think you’ve merely stopped a business deal. That is not the case! The Arabs have taken billions of dollars out of this country, and now they must put it back! It is ebb and flow, tidal gravity! It is ecological balance!
“You are an old man who thinks in terms of nations and peoples. There are no nations. There are no peoples. There are no Russians. There are no Arabs. There are no third worlds. There is no West. There is only one holistic system of systems, one vast and immane, interwoven, interacting, multivariate, multinational dominion of dollars. Petro-dollars, electro-dollars, multi-dollars, Reich marks, rins, rubles, pounds, and shekels.
“It is the international system of currency which determines the totality of life on this planet. That is the natural order of things today. That is the atomic and subatomic and galactic structure of things today! And you have meddled with the primal forces of nature, and you… will… atone!
“Am I getting through to you, Mr. Beale?
“You get up on your little twenty-one inch screen and howl about America and democracy. There is no America. There is no democracy. There is only IBM, and ITT, and AT&T, and DuPont, Dow, Union Carbide, and Exxon. Those are the nations of the world today.
“What do you think the Russians talk about in their councils of state, Karl Marx? They get out their linear programming charts, statistical decision theories, minimax solutions, and compute the price-cost probabilities of their transactions and investments, just like we do. We no longer live in a world of nations and ideologies, Mr. Beale. The world is a college of corporations, inexorably determined by the immutable bylaws of business.
“The world is a business, Mr. Beale. It has been since man crawled out of the slime. And our children will live, Mr. Beale, to see that… perfect world… in which there’s no war or famine, oppression or brutality. One vast and ecumenical holding company, for whom all men will work to serve a common profit, in which all men will hold a share of stock. All necessities provided, all anxieties tranquilized, all boredom amused.
“And I have chosen you, Mr. Beale, to preach this evangel.”
https://theshadowzone.wordpress.com/2012/12/20/network-1976-review/